Obstetrics Simplified - Diaa M. EI-Mowafi
Jaundice in Pregnancy
| Disease | Time of Onset | Cause | Main Symptoms | Prognosis |
| Recurrent cholestatic jaundice of pregnancy | Usually last quarter | Oestrogen. Familial. |
Pruritus. Mild jaundice. |
Spontaneous resolution but recurs with pregnancy and hormonal therapy. |
| Acute fatty liver | Last quarter | Protein malnutrition. Eclampsia & pre- eclampsia. |
Severe vomiting. Abdominal pain. Haematemesis. |
Poor, maternal mortality 80%. |
| Viral hepatitis | Any | Viral. | Malaise. Anorexia. Vomiting. Pyrexia. Upper abdominal pain. Hepatomegaly. |
Good, but poor in malnutrition. |
| Cholecystitis | Any | Biliary obstruction. | Pain. Vomiting. Malaise. Jaundice. |
Good, surgical treatment rarely required. |
| Acute pancreatitis | Common in late pregnancy | Severe pain. Vomiting. Hypotension. Rapid pulse. |
High mortality 20%. | |
| Haemolytic anaemia | Any | Drugs. Anaesthesia. Incompatible blood transfusion. |
Anaemia. Jaundice. |
Good if proper diagnosis and treatment is taken. |