Menstruation disturbances, female gonadal disorders : Guidelines, reviews, epidemiology

Menstruation disturbances, female gonadal disorders

Guidelines, reviews, epidemiology

Abnormal uterine bleeding, menorrhagia - Amenorrhea, premature ovarian insufficiency - Dysmenorrhea, chronic pelvic pain - Exercise-associated amenorrhea, female athlete triad - Hyperprolactinemia, galactorrhea - Polycystic ovary syndrome, polyendocrine metabolic ovarian syndrome - Premenstrual syndrome

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Abnormal uterine bleeding, menorrhagia

Australia
- Australian Commission on Safety and Quality in Health Care
  - Heavy Menstrual Bleeding Clinical Care Standard [2024]
- Australian Journal of General Practice
  - Temporal trends in tranexamic acid prescribing by Australian general practice registrars for heavy menstrual bleeding [2025]
  - Management of heavy menstrual bleeding in Australian general practice: An analysis of BEACH data [2021]
- SA Health
  - Abnormal Uterine Bleeding
Brazil
- European Journal of Contraception & Reproductive Health Care
  - The SARS-CoV-2 (COVID-19) pandemic and diagnosis and treatment of women with abnormal uterine bleeding: findings from Brazil [2025]
- International Journal of Gynecology & Obstetrics
  - Menstrual pattern and self-reported abnormal uterine bleeding in Brazilian adolescents: A multicenter cross-sectional study [2025]
- PLoS ONE
  - Prevalence of abnormal uterine bleeding in Brazilian women: Association between self-perception and objective parameters [2023]
Canada
- Alberta Health Services
  - Bleeding After Pregnancy Primary Care Pathway
  - Adolescent Abnormal Uterine Bleeding Primary Care Pathway
  - Abnormal Uterine Bleeding Primary Care Pathway
- CMAJ Open
  - Outpatient uterine assessment and treatment unit in patients with abnormal uterine bleeding: an economic modelling study [2020]
- Ontario Health
  - Levonorgestrel-Releasing Intrauterine System (52 mg) for Idiopathic Heavy Menstrual Bleeding: A Health Technology Assessment [2016]
- Society of Obstetricians and Gynaecologists of Canada
  - Endometrial Ablation in the Management of Abnormal Uterine Bleeding [2024]
  - Diagnosis and Management of Endometrial Polyps [2024]
  - Classification and Management of Endometrial Hyperplasia [2019]
  - Gynaecological and Obstetric Management of Women With Inherited Bleeding Disorders [2018]
  - Abnormal Uterine Bleeding in Pre-Menopausal Women [2018]
Canada, Europe
- Facts, Views & Vision in ObGyn
  - An overview of International AUB/HMB Guidelines [2023]
China
- European Journal of Surgical Oncology
  - Chinese guidelines on the management of endometrial hyperplasia [2024]
France
- PLoS ONE
  - The surgical treatment of idiopathic abnormal uterine bleeding: An analysis of 88 000 patients from the French exhaustive national hospital discharge database from 2009 to 2015 [2019]
- Vaccine
  - Risk of heavy menstrual bleeding following COVID-19 vaccination: A nationwide case-control study [2024]
Germany
- Institute for Quality and Efficiency in Health Care
  - Radiofrequency endometrial ablation for menorrhagia using a mesh electrode [2022]
High-income countries
- Medicina
  - Quality of Life, Anxiety and Depression in Women Treated with Hysteroscopic Endometrial Resection or Ablation for Heavy Menstrual Bleeding: Systematic Review and Meta-Analysis of Randomized Controlled Trials [2022]
Hong Kong
- Hong Kong College of Obstetricians and Gynaecologists
  - 2020 Hong Kong College of Obstetricians and Gynaecologists guideline on investigations of premenopausal women with abnormal uterine bleeding [2020]
  - Guidelines on Clinical Management of Endometrial Hyperplasia [2015]
India
- Federation of Obstetric and Gynecological Societies of India
  - Management of Abnormal Uterine Bleeding [2024]
  - Management Guidelines of Abnormal Uterine Bleeding in Reproductive Period. Evidence-based Good Clinical Practice Recommendations for Indian women [2016]
International
- Advances in Therapy
  - A Review of Clinical Guidelines on the Management of Iron Deficiency and Iron-Deficiency Anemia in Women with Heavy Menstrual Bleeding [2020]
- Blood Advances
  - Gynecologic and obstetric management of women with von Willebrand disease: summary of 3 systematic reviews of the literature [2022]
- BMC Women's Health
  - Pictorial methods to assess heavy menstrual bleeding in research and clinical practice: a systematic literature review [2020]
- BMJ
  - Second generation endometrial ablation techniques for heavy menstrual bleeding: network meta-analysis [2012]
- Cochrane Database of Systematic Reviews
  - Interventions for heavy menstrual bleeding; overview of Cochrane reviews and network meta-analysis [2022]
  - Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding [2021]
  - Progestogen-releasing intrauterine systems for heavy menstrual bleeding [2020]
  - Levonorgestrel-releasing intrauterine system for endometrial hyperplasia [2020]
  - Interventions commonly available during pandemics for heavy menstrual bleeding: an overview of Cochrane Reviews [2020]
  - Non-steroidal anti-inflammatory drugs for heavy menstrual bleeding [2019]
  - Endometrial resection and ablation techniques for heavy menstrual bleeding [2019]
- Gynecological Endocrinology
  - Unmet needs in abnormal uterine bleeding due to ovulatory dysfunction [2024]
- International Federation of Gynecology and Obstetrics
  - Our path from abnormal uterine bleeding and iron deficiency to impaired fetal development: A long and winding road [2023]
  - Abnormal uterine bleeding: A well-travelled path to iron deficiency and anemia [2020]
  - The two FIGO systems for normal and abnormal uterine bleeding symptoms and classification of causes of abnormal uterine bleeding in the reproductive years: 2018 revisions Library [2018]
  - FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age [2011]
- International Journal of Gynecology & Obstetrics
  - Therapeutic options for the management of abnormal uterine bleeding [2023]
  - Reflections on access to care for heavy menstrual bleeding: Past, present, and in times of the COVID-19 pandemic [2023]
  - Heavy menstrual bleeding, iron deficiency, and iron deficiency anemia: Framing the issue [2023]
  - Contemporary evaluation of women and girls with abnormal uterine bleeding: FIGO Systems 1 and 2 [2023]
- International Society on Thrombosis and Haemostasis
  - Standardizing care to manage bleeding disorders in adolescents with heavy menses-A joint project from the ISTH pediatric/neonatal and women's health SSCs [2020]
- Journal of Obstetrics and Gynaecology of India
  - Diagnosis and Management of Formerly Called “Dysfunctional Uterine Bleeding” According to PALM-COEIN FIGO Classification and the New Guidelines [2014]
Ireland
- Ireland's Health Services
  - The investigation and management of menorrhagia [2015]
Israel
- Reproductive Sciences
  - Abnormal Uterine Bleeding Among COVID-19 Vaccinated and Recovered Women: a National Survey [2023]
Japan
- Journal of Obstetrics and Gynaecology Research
  - National survey of abnormal uterine bleeding according to the FIGO classification in Japan [2023]
Low and middle income countries
- BMC Women's Health
  - The prevalence and burden of heavy menstrual bleeding, and market access barriers of medical interventions with a focus on low- and middle-income countries: a scoping review [2025]
Malaysia
- Medical Journal of Malaysia
  - Evaluation and management of abnormal uterine bleeding [2022]
Netherlands
- American Journal of Obstetrics & Gynecology
  - Levonorgestrel-releasing intrauterine system versus endometrial ablation for heavy menstrual bleeding [2021]
- BJOG: An International Journal of Obstetrics & Gynaecology
  - The levonorgestrel intrauterine system versus endometrial ablation for heavy menstrual bleeding: a cost-effectiveness analysis [2021]
- European Journal of Obstetrics & Gynecology and Reproductive Biology
  - Practice variation in the stepped care approach to idiopathic heavy menstrual bleeding: A population-based study [2023]
- Journal of Thrombosis and Haemostasis
  - High prevalence of heavy menstrual bleeding in women with rare bleeding disorders in the Netherlands: retrospective data from the RBiN study [2023]
Poland
- Ginekologia Polska
  - Recommendations of the Group of Experts of the Polish Society of Gynecologists and Obstetricians regarding abnormal uterine bleeding in adolescents [2020]
Republic of Korea
- Journal of Korean Medical Science
  - Comprehensive Analysis of Iron Deficiency Anemia and Its Related Disorders in Premenopausal Women Based on a Propensity Score Matching Case Control Study Using National Health Insurance Service Database in Korea [2023]
- Obstetrics & Gynecology Science
  - Therapy of heavy menstrual bleeding in Korea: Subanalysis and results from a multinational clinical trial in the Asian region investigating the levonorgestrel-releasing intrauterine system versus conventional therapy [2015]
South Africa
- South African Society of Obstetricians and Gynaecologists
  - Guideline for the Management of Abnormal Uterine Bleeding (AUB) [2020]
Taiwan
- Taiwanese Journal of Obstetrics and Gynecology
  - Medical treatment for heavy menstrual bleeding [2015]
United Kingdom
- Academy of Medical Royal Colleges
  - Hysterectomy for heavy menstrual bleeding [2024]
  - Dilatation & curettage for heavy menstrual bleeding [2024]
- BMC Health Services Research
  - The delivery of heavy menstrual bleeding services in England and Wales after publication of national guidelines: a survey of hospitals [2013]
- BMJ Open
  - Factors associated with receiving surgical treatment for menorrhagia in England and Wales: findings from a cohort study of the National Heavy Menstrual Bleeding Audit [2019]
  - Sociodemographic differences in symptom severity and duration among women referred to secondary care for menorrhagia in England and Wales: a cohort study from the National Heavy Menstrual Bleeding Audit [2018]
- Health Technology Assessment
  - Rates of medical or surgical treatment for women with heavy menstrual bleeding: the ECLIPSE trial 10-year observational follow-up study [2023]
  - Laparoscopic supracervical hysterectomy compared with second-generation endometrial ablation for heavy menstrual bleeding: the HEALTH RCT [2019]
- National Institute for Health and Care Excellence
  - Heavy menstrual bleeding: assessment and management [2021]
  - 2021 exceptional surveillance of heavy menstrual bleeding: assessment and management (NICE guideline NG88) [2021]
  - Heavy menstrual bleeding (Quality standard) [2020]
  - Heavy menstrual bleeding
- Obstetrics, Gynaecology and Reproductive Medicine
  - Heavy menstrual bleeding management during the Covid pandemic [2021]
- PLoS ONE
  - Levonorgestrel-Releasing Intrauterine System vs. Usual Medical Treatment for Menorrhagia: An Economic Evaluation Alongside a Randomised Controlled Trial [2014]
- Right Decisions
  - Menstrual Disorders including Heavy Menstrual Bleeding (HMB)
- Royal College of Obstetricians and Gynaecologists
  - Joint RCOG, BSGE and BGCS guidance for the management of abnormal uterine bleeding in the evolving Coronavirus (COVID-19) pandemic [2020]
  - Management of Endometrial Hyperplasia [2016]
United States
- American College of Obstetricians and Gynecologists
  - Options for Prevention and Management of Menstrual Bleeding in Adolescent Patients Undergoing Cancer Treatment [2021]
  - Screening and Management of Bleeding Disorders in Adolescents With Heavy Menstrual Bleeding [2019]
  - Von Willebrand Disease in Women [2013]
  - Management of Acute Abnormal Uterine Bleeding in Nonpregnant Reproductive-Aged Women [2013]
- American College of Radiology
  - Abnormal Uterine Bleeding
- American Family Physician
  - Abnormal Uterine Bleeding in Premenopausal Women [2019]
- American Journal of Obstetrics & Gynecology
  - Abnormal uterine bleeding diagnoses and care following COVID-19 vaccination [2024]
- American Society for Reproductive Medicine
  - Abnormal Uterine Bleeding
- Archives of Gynecology and Obstetrics
  - Increasing utilization of intrauterine device insertion at hysteroscopic endometrial evaluation for patients with endometrial hyperplasia [2024]
- Centers for Disease Control and Prevention
  - Bleeding Disorders in Women
- Drug Safety
  - Comparative Risk Assessment of Severe Uterine Bleeding Following Exposure to Direct Oral Anticoagulants: A Network Study Across Four Observational Databases in the USA [2021]
- Hematology: the American Society of Hematology Education Program
  - von Willebrand disease and heavy menstrual bleeding: when and how to test [2024]
  - Evaluation and management of heavy menstrual bleeding in adolescents: the role of the hematologist [2018]
- Mayo Clinic Proceedings
  - Evaluation and Management of Abnormal Uterine Bleeding [2019]
- North American Society for Pediatric and Adolescent Gynecology
  - NASPAG Clinical Consensus: Use of Tranexamic Acid in the Treatment of Heavy Menstrual Bleeding [2025]
- Permanente Journal
  - Acute Uterine Bleeding Unrelated to Pregnancy: A Southern California Permanente Medical Group Practice Guideline [2013]
- Society of Gynecologic Surgeons
  - Nonsurgical management of heavy menstrual bleeding: a systematic review [2013]
  - A systematic review comparing hysterectomy with less-invasive treatments for abnormal uterine bleeding [2012]
  - Systematic review highlights difficulty interpreting diverse clinical outcomes in abnormal uterine bleeding trials [2011]
- StatPearls
  - Menorrhagia
{Related topics}
- Topic
  - Uterine fibroids
  - Menopause, hormone replacement therapy: abnormal bleeding
  - Gynecologic ultrasound
  - Endometriosis
  - Adenomyosis

Amenorrhea, premature ovarian insufficiency

Dysmenorrhea, chronic pelvic pain

Exercise-associated amenorrhea, female athlete triad

Hyperprolactinemia, galactorrhea

Polycystic ovary syndrome, polyendocrine metabolic ovarian syndrome

Premenstrual syndrome