☰ Menu

Module 3: Epidemiologic studies

Module 3

Module 3: Epidemiologic studies

Training course in research methodology, research protocol development and scientific writing 2024

September 18, 2024 - Geneva

Assignment

Part 1

Question 1: Read the abstract and method sections of the cohort study below.

Lin J, Gu W, Huang H. Effects of Paternal Obesity on Fetal Development and Pregnancy Complications: A Prospective Clinical Cohort Study. Front Endocrinol (Lausanne). 2022 Mar 14;13:826665.

Answer the following questions (8 marks):

1.1 What was the cohort in this study?

1.2 Identify with reason the study type based on time (prospective/retrospective/cross sectional).

1.3 What were the exposure and outcome variables?

1.4 Mention two advantages and two disadvantages of this study design.

Question 2: Read the abstract and method sections of the case-control study below.

El Najar A, Abu Hamad K. Hospital-based case-control study of risk factors for early neonatal mortality in the Gaza Strip. East Mediterr Health J. 2023 May 31;29(5):317-323.

Answer the following questions (6.5 marks):

2.1 Define the cases and controls in this study.

2.2 Were the cases matched with controls?

2.3 Mention the risk factors/exposures studied?

2.4 Why is matching used in a case control study?

Question 3: Go over the cross-sectional study below.

Zeng Y, Yin L, Yin X, Zhao D. Association of triglyceride-glucose index levels with gestational diabetes mellitus in the US pregnant women: a cross-sectional study. Front Endocrinol (Lausanne). 2023 Oct 10;14:1241372.

Answer the following questions (5.5 marks):

3.1  What were the inclusion and exclusion criteria for the study?

3.2  What were the main dependent and the main independent variables?

3.3 What factor(s) did the researchers considered when examining the association between the variables?

Question 4: Read the abstract and method of the randomized control trial below.

Zhou Y, Bai Z, Zhang W, Xu S, Feng Y, Li Q, Li L, Ping A, Chen L, Wang S, Duan K. Effect of Dexmedetomidine on Postpartum Depression in Women With Prenatal Depression. JAMA Netw Open. 2024 Jan 25;7(1):e2353252.

Answer the following questions (5 marks):

4.1 What were the treatment in the intervention and control/placebo group?

4.2 What was the main/primary outcome measured in the study?

4.3 Was any blinding used? If yes, what type?

Part 2

Reflect over the topic, question and study design for your research protocol, revise if necessary and submit to your coach for review and feedback.