Tuberculosis

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Latent tuberculosis

Afghanistan

• PLoS ONE
  • Prevalence of latent tuberculosis infection among health workers in Afghanistan: A cross-sectional study [2021]

Asia

• Immunity, Inflammation and Disease
  • Prevalence of latent tuberculosis infection in Asian nations: A systematic review and meta-analysis [2024]

Australia

• Australian Journal of General Practice
  • Latent tuberculosis in the general practice context [2020]

• Department of Health and Aged Care
  • National position statement for the management of latent tuberculosis infection [2017]

• Queensland Health
  • Management of Latent Tuberculosis in Adults

Australia, New Zealand

• Tuberculosis Research and Treatment
  • Management of Latent Tuberculosis Infections in Australia and New Zealand: A Review of Current Practice [2010]

Austria

• Wiener klinische Wochenschrift
  • National consensus statement by the Austrian Societies for Rheumatology, Pulmonology, Infectiology, Dermatology and Gastroenterology regarding the management of latent tuberculosis and the associated utilization of biologic and targeted synthetic disease modifying antirheumatic drugs (DMARDs) [2022]

Austria, Germany, Switzerland

• PLoS ONE
  • Management of childhood and adolescent latent tuberculous infection (LTBI) in Germany, Austria and Switzerland [2021]

Brazil

• BMJ Global Health
  • Determinants of losses in the latent tuberculosis infection cascade of care in Brazil [2021]

Canada

• BMC Public Health
  • Recommendations for the screening of paediatric latent tuberculosis infection in indigenous communities: a systematic review of screening strategies among high-risk groups in low-incidence countries [2018]

• BMJ Open
  • Burden of non-adherence to latent tuberculosis infection drug therapy and the potential cost-effectiveness of adherence interventions in Canada: a simulation study [2017]

• Canadian Agency for Drugs and Technologies in Health
  • Occupational Screening for Latent Tuberculosis Infection [2021]
  • Interferon Gamma Release Assay for the Identification of Latent Tuberculosis Infection in Rural and Remote Settings [2021]
  • Latent Tuberculosis Infection Testing in People with Compromised Immunity Prior to Biologic Therapy: A Review of Diagnostic Accuracy, Clinical Utility, and Guidelines [2020]

• Public Health Agency of Canada
  • Latent tuberculosis infection: An overview [2017]
  • Recommendations on interferon gamma release assays for the diagnosis of latent tuberculosis infection - 2010 update [2010]

China

• International Journal of Infectious Diseases
  • Management of Latent Tuberculosis Infection in China: Exploring solutions suitable for high-burden countries [2020]

• Journal of Thoracic Disease
  • Risk of prevalence of latent tuberculosis infection in health care workers-an idiographic meta-analysis from a Chinese perspective [2021]

• PLoS ONE
  • Latent Tuberculosis Infection and Occupational Protection among Health Care Workers in Two Types of Public Hospitals in China [2014]

Colombia

• BMJ Open
  • Cost-effectiveness analysis comparing QuantiFERON test and tuberculin skin test for the diagnosis of latent tuberculosis infection in immunocompetent children under 15 years of age in Colombia [2025]

• Multiple Sclerosis Journal - Experimental, Translational and Clinical
  • Diagnosis and treatment of latent tuberculosis in patients with multiple sclerosis, expert consensus. On behalf of the Colombian Association of Neurology, Committee of Multiple Sclerosis [2018]

Europe

• European Centre for Disease Prevention and Control
  • Review of reviews and guidelines on target groups, diagnosis, treatment and programmatic issues for implementation of latent tuberculosis management [2018]
  • Programmatic management of latent tuberculosis infection in the European Union [2018]
  • Mathematical modelling of programmatic screening strategies for latent tuberculosis infection in countries with low tuberculosis incidence [2018]
  • Cost-effectiveness analysis of programmatic screening strategies for latent tuberculosis infection in the EU/EEA [2018]
  • Management of latent tuberculosis infection

• EuroSurveillance
  • Country-specific approaches to latent tuberculosis screening targeting migrants in EU/EEA countries: A survey of national experts, September 2019 to February 2020 [2022]
  • The effectiveness and cost-effectiveness of screening for latent tuberculosis among migrants in the EU/EEA: a systematic review [2018]
  • Identifying components for programmatic latent tuberculosis infection control in the European Union [2016]

Germany

• International Journal of Environmental Research and Public Health
  • Latent Tuberculosis Infection among Health Workers in Germany—A Retrospective Study on Progression Risk and Use of Preventive Therapy [2021]

India

• Indian Journal of Medical Ethics
  • Ethical issues in expanding latent TB management in high burden countries [2020]

• Lung India
  • Management of latent tuberculosis infection: An evidence-based approach [2015]

International

• BMC Infectious Diseases
  • Interferon-gamma release assay levels and risk of progression to active tuberculosis: a systematic review and dose-response meta-regression analysis [2021]

• BMC Public Health
  • Global trends and gaps in research related to latent tuberculosis infection [2020]

• BMJ Open
  • Screening and prevention for latent tuberculosis in immunosuppressed patients at risk for tuberculosis: a systematic review of clinical practice guidelines [2018]

• European Respiratory Journal
  • Management of latent Mycobacterium tuberculosis infection: WHO guidelines for low tuberculosis burden countries [2015]

• International Journal of Infectious Diseases
  • Prevalence trends of latent tuberculosis infection at the global, regional, and country levels from 1990-2019 [2022]
  • Preventive therapy for latent tuberculosis infection—the promise and the challenges [2017]

• Journal of Public Health
  • How can we improve latent tuberculosis infection management using behaviour change wheel: a systematic review [2023]

• Lancet Infectious Diseases
  • Initiation and completion of treatment for latent tuberculosis infection in migrants globally: a systematic review and meta-analysis [2021]
  • Global burden of latent multidrug-resistant tuberculosis: trends and estimates based on mathematical modelling [2019]

• PLoS Medicine
  • The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling [2016]

• Scientific Reports
  • Efficacy of anti-tuberculosis drugs for the treatment of latent tuberculosis infection: a systematic review and network meta-analysis [2023]

Ireland

• Irish Journal of Medical Science
  • Systematic review of latent tuberculosis infection research to inform programmatic management in Ireland [2022]

Israel

• Israel Medical Association Journal
  • Interferon Gamma Release Assay-Guided Latent Tuberculosis Prophylaxis in Israel [2015]

Japan

• BMC Infectious Diseases
  • Trend and treatment outcomes of latent tuberculosis infection among migrant persons in Japan: retrospective analysis of Japan tuberculosis surveillance data [2021]

• Kekkaku (Tuberculosis)
  • Treatment guidelines for latent tuberculosis infection [2014]

• PLoS ONE
  • Trend and treatment status of latent tuberculosis infection patients in Japan – Analysis of Japan TB Surveillance data [2017]

• Western Pacific Surveillance and Response Journal
  • Epidemiology of latent tuberculosis infection in Japan-born and foreign-born children in Japan [2023]

Kenya

• Ministry of Health Kenya
  • Guidelines on the programmatic management of tuberculosis preventive therapy (PMTPT) [2020]

Low and middle income countries

• Health Science Reports
  • How are high burden countries implementing policies and tools for latent tuberculosis infection? A survey of current practices and barriers [2020]

• PLoS ONE
  • Prevalence of Latent Tuberculosis among Health Care Workers in High Burden Countries: A Systematic Review and Meta-Analysis [2016]

Malaysia

• Ministry of Health Malaysia
  • Programmatic management of latent tuberculosis infection [2019]

Middle East, North Africa

• Pulmonary Medicine
  • Prevalence of Latent Tuberculosis Infection in the Middle East and North Africa: A Systematic Review [2021]

Norway

• BMC Infectious Diseases
  • Treatment completion for latent tuberculosis infection in Norway: a prospective cohort study [2018]

• BMJ Open
  • Immigrant screening for latent tuberculosis infection: numbers needed to test and treat, a Norwegian population-based cohort study [2019]

Philippines

• Department of Health Philippines
  • Guidance on the Use of Fixed-Dosed Combination for Tuberculosis Preventive Treatment (TPT) [2021]

Republic of Korea

• Epidemiology and Health
  • An opposing view on including high school students in a latent tuberculosis infection control program in Korea [2017]

• Frontiers in Public Health
  • Prevalence of latent tuberculosis infection among participants of the national LTBI screening program in South Korea - A problem of low coverage rate with current LTBI strategy [2023]

• Journal of Preventive Medicine and Public Health
  • Proposal to Revise the Screening Test for Latent Tuberculosis Infection in Close Contacts at Elementary Schools in Korea [2019]

• Korean Journal of Internal Medicine
  • Adverse drug reactions following treatment of latent tuberculosis infection: a linked national tuberculosis surveillance with claims database [2024]

• Tuberculosis and Respiratory Diseases
  • Treatment of Latent Tuberculosis Infection and Its Clinical Efficacy [2018]
  • Diagnosis and Treatment of Latent Tuberculosis Infection in Healthcare Workers [2016]
  • Diagnosis and Treatment of Latent Tuberculosis Infection [2015]

Rwanda

• Ministry of Health Rwanda
  • Tuberculosis Preventive Treatment Guidelines [2022]

Saudi Arabia

• Saudi Thoracic Society
  • Saudi guidelines for testing and treatment of latent tuberculosis infection [2010]

Singapore

• BMJ Open
  • Cross-sectional study of prevalence and risk factors, and a cost-effectiveness evaluation of screening and preventive treatment strategies for latent tuberculosis among migrants in Singapore [2021]

• International Journal of Infectious Diseases
  • Prevalence of and risk factors associated with latent tuberculosis in Singapore: A cross-sectional survey [2018]

Spain

• Revista Española de Sanidad Penitenciaria
  • Guidelines on controlling latent tuberculosis infection to support tuberculosis elimination [2021]

Sri Lanka

• Inquiry
  • Cost-Effectiveness Analysis of a Latent Tuberculosis Screening Program Among Healthcare Personnel [2025]

• Ministry of Health Sri Lanka
  • National Guideline on Latent Tuberculosis Infection (LTBI) Management [2021]

Sweden

• International Journal of Infectious Diseases
  • Prevalence of Latent TB and Effectiveness of BCG Vaccination Against Latent Tuberculosis: An Observational Study [2021]

United Kingdom

• BMC Health Services Research
  • "It's too hard" - the management of latent TB in under-served populations in the UK: a qualitative study [2022]

• Lancet Public Health
  • Effectiveness of nationwide programmatic testing and treatment for latent tuberculosis infection in migrants in England: a retrospective, population-based cohort study [2022]

• NHS England
  • National latent tuberculosis infection testing and treatment programme

• Public Health England
  • Latent tuberculosis testing and treatment programme for migrants
  • Latent TB infection (LTBI): testing and treatment

United States

• Agency for Healthcare Research and Quality
  • Screening for Latent Tuberculosis Infection in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force [2023]

• American Journal of Nursing
  • Tuberculosis: A New Screening Recommendation and an Expanded Approach to Elimination in the United States [2017]

• Centers for Disease Control and Prevention
  • Tuberculosis Testing and Latent Tuberculosis Infection Treatment Practices Among Health Care Providers — United States, 2020–2022 [2023]
  • Trends in tuberculosis clinicians' adoption of short-course regimens for latent tuberculosis infection [2023]
  • Guidelines for the Treatment of Latent Tuberculosis Infection: Recommendations from the National Tuberculosis Controllers Association and CDC, 2020 [2020]
  • Update of Recommendations for Use of Once-Weekly Isoniazid-Rifapentine Regimen to Treat Latent Mycobacterium tuberculosis Infection [2018]
  • Simple Estimates for Local Prevalence of Latent Tuberculosis Infection, United States, 2011–2015 [2018]
  • Treatment Regimens for Latent TB Infection
  • Latent TB Infection Resource Hub

• Clinical Infectious Diseases
  • Prevalence of Latent Tuberculosis Infection Among Non-US-Born Persons by Country of Birth-United States, 2012-2017 [2021]

• JAMA
  • Management of Latent Tuberculosis Infection [2023]

• Medicine
  • A cross-sectional study of latent tuberculosis infection, insurance coverage, and usual sources of health care among non-US-born persons in the United States [2021]

• National Tuberculosis Coalition of America
  • Testing and Treatment of Latent Tuberculosis Infection in the United States: A Clinical Guide for Health Care Providers and Public Health Programs [2025]

• PLoS ONE
  • State-level prevalence estimates of latent tuberculosis infection in the United States by medical risk factors, demographic characteristics and nativity [2021]

• U.S. Preventive Services Task Force
  • Latent Tuberculosis Infection in Adults: Screening [2023]

WHO

• World Health Organization
  • Meeting of the Implementation Core Group of WHO Global Task Force on Latent TB Infection and country stakeholders on implementation tools and joint TB and HIV programming to scale up TB preventive treatment [2018]
  • Latent tuberculosis infection: updated and consolidated guidelines for programmatic management [2018]

{Related topics}

• Topic
  • Tuberculosis