Maternal and neonatal infections

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Malaria in pregnancy

Afghanistan

• Malaria Journal
  • Towards a strategy for malaria in pregnancy in Afghanistan: analysis of clinical realities and women’s perceptions of malaria and anaemia [2015]

Africa

• Malaria Journal
  • Has doxycycline, in combination with anti-malarial drugs, a role to play in intermittent preventive treatment of Plasmodium falciparum malaria infection in pregnant women in Africa? [2018]
  • Rationale for short course primaquine in Africa to interrupt malaria transmission [2013]

• WHO African Region
  • A strategic framework for malaria prevention and control during pregnancy in the African Region [2004]
  • Malaria

• World Health Organization
  • Strategy to respond to antimalarial drug resistance in Africa [2022]

Africa, Western Pacific

• BMJ Open
  • Maternal Malaria and Malnutrition (M3) initiative, a pooled birth cohort of 13 pregnancy studies in Africa and the Western Pacific [2016]

Asia, Sub-Saharan Africa

• Lancet
  • Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis [2023]

Benin

• American Journal of Tropical Medicine and Hygiene
  • Prevention of Malaria during Pregnancy: Assessing the Effect of the Distribution of IPTp Through the National Policy in Benin [2011]

Bolivia

• Emerging Infectious Diseases
  • Plasmodium vivax Malaria during Pregnancy, Bolivia [2013]

Brazil

• Memórias do Instituto Oswaldo Cruz
  • A decade of malaria during pregnancy in Brazil: what has been done concerning prevention and management [2014]

• PLoS Neglected Tropical Diseases
  • Costs Associated with Malaria in Pregnancy in the Brazilian Amazon, a Low Endemic Area Where Plasmodium vivax Predominates [2016]

Burkina Faso

• Infection and Immunity
  • Associations between prenatal malaria exposure, maternal antibodies at birth, and malaria susceptibility during the first year of life in Burkina Faso [2023]

• Malaria Journal
  • Asymptomatic malaria and anaemia among pregnant women during high and low malaria transmission seasons in Burkina Faso: household-based cross-sectional surveys in Burkina Faso, 2013 and 2017 [2021]

• Scientific Reports
  • Bayesian Spatiotemporal Modeling of Routinely Collected Data to Assess the Effect of Health Programs in Malaria Incidence During Pregnancy in Burkina Faso [2020]

• Spatial and Spatio-temporal Epidemiology
  • Severe-malaria infection and its outcomes among pregnant women in Burkina Faso health-districts: Hierarchical Bayesian space-time models applied to routinely-collected data from 2013 to 2018 [2020]

Burundi

• Malaria Journal
  • The lead-up to epidemic transmission: malaria trends and control interventions in Burundi 2000 to 2019 [2021]

China

• PLoS Neglected Tropical Diseases
  • Congenital Malaria in China [2014]

Colombia

• PLoS ONE
  • Meta-analysis of the prevalence of malaria associated with pregnancy in Colombia 2000–2020 [2021]

Democratic Republic of Congo, Malawi

• American Journal of Tropical Medicine and Hygiene
  • Malaria-Related Psychosocial Factors, Past Antenatal Care-Seeking Behaviors, and Future Antenatal Care-Seeking Intentions by Maternal Age in Malawi and Democratic Republic of the Congo [2023]

East Africa

• BMC Public Health
  • Utilization of insecticide-treated nets among pregnant women in East Africa: evidence from a systematic review and meta-analysis [2024]

• Malaria Journal
  • The impact of malaria during pregnancy on low birth weight in East-Africa: a topical review [2021]

Ecuador

• Biomédica
  • Prevalence of gestational malaria in Ecuador [2022]

Ethiopia

• Journal of Parasitology Research
  • The Prevalence of Malaria among Pregnant Women in Ethiopia: A Systematic Review and Meta-Analysis [2019]

• Malaria Journal
  • Insecticide-treated bed net utilization and associated factors among pregnant women in Ethiopia: a systematic review and meta-analysis [2023]

Europe

• Travel Medicine and Infectious Disease
  • Imported malaria in pregnancy in Europe: A systematic review of the literature of the last 25 years [2023]

Gabon

• BMC Pregnancy and Childbirth
  • Antenatal care visit attendance, intermittent preventive treatment and bed net use during pregnancy in Gabon [2013]

Ghana

• Demographic and Health Surveys
  • Individual- and Community-level Correlates of Intermittent Preventive Treatment of Malaria in Pregnancy in Ghana [2023]

• Malaria Journal
  • Successful implementation of ITN distribution through health facilities in Ghana [2023]
  • Trends of malaria infection in pregnancy in Ghana over the past two decades: a review [2022]
  • Malaria in pregnancy control and pregnancy outcomes: a decade's overview using Ghana's DHIMS II data [2022]
  • Impact of insecticide-treated nets and indoor residual spraying on self-reported malaria prevalence among women of reproductive age in Ghana: implication for malaria control and elimination [2022]
  • Managing intermittent preventive treatment of malaria in pregnancy challenges: an ethnographic study of two Ghanaian administrative regions [2020]

India

• Frontiers in Global Women's Health
  • Prevalence of Pregnancy Associated Malaria in India [2022]

Indonesia

• Malaria Journal
  • Performance of four HRP-2/pLDH combination rapid diagnostic tests and field microscopy as screening tests for malaria in pregnancy in Indonesia: a cross-sectional study [2015]

International

• BMC Medicine
  • Pregnancy outcomes and risk of placental malaria after artemisinin-based and quinine-based treatment for uncomplicated falciparum malaria in pregnancy: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis [2020]

• Cochrane Database of Systematic Reviews
  • Mefloquine for preventing malaria in pregnant women [2018]

• Heliyon
  • Systematic review of microeconomic analysis of pregnancy-associated malaria [2020]

• Lancet Infectious Diseases
  • Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis [2020]

• Malaria Journal
  • Drug treatment and prevention of malaria in pregnancy: a critical review of the guidelines [2021]
  • Systematic review of statistical methods for safety data in malaria chemoprevention in pregnancy trials [2020]
  • Epidemiology of clinical congenital and neonatal malaria in endemic settings: a systematic review and meta-analysis [2020]

• Médecins Sans Frontières
  • Malaria in pregnancy: a call for a safe, efficient, and patient-centred approach to first-trimester treatment [2018]

• PLoS Medicine
  • Women's Access and Provider Practices for the Case Management of Malaria during Pregnancy: A Systematic Review and Meta-Analysis [2014]

• SBCC Implementation Kits
  • Malaria in Pregnancy Strategy Guidance

• Scientific Reports
  • Global genetic diversity of var2csa in Plasmodium falciparum with implications for malaria in pregnancy and vaccine development [2018]

Kenya

• Malaria Journal
  • Healthcare provider and drug dispenser knowledge and adherence to guidelines for the case management of malaria in pregnancy in the context of multiple first-line artemisinin-based combination therapy in western Kenya [2023]
  • Determinants of utilization of malaria preventive measures during pregnancy among women aged 15 to 49 years in Kenya: an analysis of the Malaria Indicator Survey 2020 [2022]
  • Effectiveness of the delivery of interventions to prevent malaria in pregnancy in Kenya [2016]

• PLoS ONE
  • Knowledge and Adherence to the National Guidelines for Malaria Case Management in Pregnancy among Healthcare Providers and Drug Outlet Dispensers in Rural, Western Kenya [2016]

Low and middle income countries

• Lancet Global Health
  • Prevalence of and risk factors for microscopic and submicroscopic malaria infections in pregnancy: a systematic review and meta-analysis [2023]

Madagascar

• Malaria Journal
  • Status of malaria in pregnancy services in Madagascar 2010-2021: a scoping review [2023]

Malawi

• BMC Health Services Research
  • Perspectives of health care providers on the provision of intermittent preventive treatment in pregnancy in health facilities in Malawi [2015]

• BMC Public Health
  • Uptake of intermittent preventive treatment for malaria during pregnancy with Sulphadoxine-Pyrimethamine in Malawi after adoption of updated World Health Organization policy: an analysis of demographic and health survey 2015–2016 [2020]

• Malaria Journal
  • The use of intermittent preventive treatment in pregnancy and insecticide-treated bed nets for malaria prevention by women of child-bearing age in eight districts in Malawi [2015]

Mali

• Journal of Parasitology
  • Factors Associated with Intermittent Preventive Treatment of Malaria During Pregnancy in Mali [2019]

• Malaria Journal
  • “There is no free here, you have to pay”: actual and perceived costs as barriers to intermittent preventive treatment of malaria in pregnancy in Mali [2016]

• PLoS ONE
  • Underreporting and Missed Opportunities for Uptake of Intermittent Preventative Treatment of Malaria in Pregnancy (IPTp) in Mali [2016]
  • Effectiveness of Antenatal Clinics to Deliver Intermittent Preventive Treatment and Insecticide Treated Nets for the Control of Malaria in Pregnancy in Mali: A Household Survey [2014]
  • Prevention of Malaria in Pregnancy with Intermittent Preventive Treatment and Insecticide Treated Nets in Mali: A Quantitative Health Systems Effectiveness Analysis [2013]
  • A Qualitative Health Systems Effectiveness Analysis of the Prevention of Malaria in Pregnancy with Intermittent Preventive Treatment and Insecticide Treated Nets in Mali [2013]

Myanmar

• PLoS ONE
  • Utilization of insecticide-treated bed nets among pregnant women in Myanmar-analysis of the 2015-2016 Demographic and Health Survey [2022]

Nigeria

• Annals of Parasitology
  • Prevalence of asymptomatic Plasmodium falciparum infection in pregnant women in Nigeria: a systematic review and meta-analysis [2020]

• BMC Pregnancy and Childbirth
  • Using Andersen's behavioral model of health care use for intermittent preventive treatment of malaria in pregnancy in Nigeria [2023]

• International Journal of Women's Health
  • Determinants of use of insecticide-treated nets among pregnant women in Nigeria [2015]

• Malaria Journal
  • Decomposition of socioeconomic inequalities in the uptake of intermittent preventive treatment of malaria in pregnancy in Nigeria: evidence from Demographic Health Survey [2021]

• Pan African Medical Journal
  • Socio-demographic and regional disparities in utilization of intermittent preventive treatment for malaria in pregnancy - Nigeria demographic health survey 2013 [2019]

• PLoS ONE
  • Geopolitical zones differentials in intermittent preventive treatment in pregnancy (IPTp) and long lasting insecticidal nets (LLIN) utilization in Nigeria [2021]

• WHO African Region
  • Report on malaria in Nigeria 2022 [2022]

Papua New Guinea

• Malaria Journal
  • Associations of maternal iron deficiency with malaria infection in a cohort of pregnant Papua New Guinean women [2022]

Republic of Guinea

• Infectious Diseases in Obstetrics and Gynecology
  • Factors Associated with Malaria Preventive Measures among Pregnant Women in Guinea [2021]

• Malaria Journal
  • Variations in the use of malaria preventive measures among pregnant women in Guinea: a secondary analysis of the 2012 and 2018 demographic and health surveys [2022]

Rwanda

• BMC Pregnancy and Childbirth
  • Mosquito bed net use and associated factors among pregnant women in Rwanda: a nationwide survey [2023]

• Clinical Infectious Diseases
  • Effectiveness of Intermittent Screening and Treatment of Malaria in Pregnancy on Maternal and Birth Outcomes in Selected Districts in Rwanda: A Cluster Randomized Controlled Trial [2023]

• PLoS ONE
  • Assessment of perinatal outcomes of pregnant women with severe versus simple malaria [2021]

Senegal

• International Journal of Environmental Research and Public Health
  • Were Women Staying on Track with Intermittent Preventive Treatment for Malaria in Antenatal Care Settings? A Cross-Sectional Study in Senegal [2022]

Sierra Leone

• Malaria Journal
  • Predictors of insecticide-treated bed nets use among pregnant women in Sierra Leone: evidence from the 2019 Sierra Leone Demographic Health Survey [2024]

South-East Asia

• BMC Medicine
  • Severe falciparum malaria in pregnancy in Southeast Asia: a multi-centre retrospective cohort study [2023]

Sub-Saharan Africa

• BMC Public Health
  • Individual, community and societal correlates of insecticide treated net use among pregnant women in sub-Saharan Africa: a multi-level analysis [2021]

• BMJ Global Health
  • Cost-effectiveness of community-based distribution of intermittent preventive treatment of malaria in pregnancy in Madagascar, Mozambique, Nigeria, and the Democratic Republic of Congo [2023]

• BMJ Open
  • Is improvement in indicators of women’s empowerment associated with uptake of WHO recommended IPTp-SP levels in sub-Saharan Africa? A multilevel approach [2021]

• Clinical Infectious Diseases
  • Burden of Malaria in Early Pregnancy: A Neglected Problem? [2014]

• eLife
  • Relationship between changing malaria burden and low birth weight in sub-Saharan Africa: A difference-in-differences study via a pair-of-pairs approach [2021]

• Global Health: Science and Practice
  • Moving malaria in pregnancy programs from neglect to priority: experience from Malawi, Senegal, and Zambia [2014]

• Health Policy and Planning
  • Adoption of evidence-based global policies at the national level: intermittent preventive treatment for malaria in pregnancy and first trimester treatment in Kenya, Malawi, Mali and The Gambia [2020]

• International Journal of Environmental Research and Public Health
  • Malaria and Helminthic Co-Infection during Pregnancy in Sub-Saharan Africa: A Systematic Review and Meta-Analysis [2022]

• Journal of Global Health
  • The association of malaria infection and gestational hypertension in Africa: Systematic review and meta-analysis [2020]

• Journal of Infectious Diseases
  • Impact of Malaria in Pregnancy on Risk of Malaria in Young Children: Systematic Review and Meta-Analyses [2020]

• Lancet Global Health
  • Community-based strategies to increase coverage of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine in sub-Saharan Africa: a systematic review, meta-analysis, meta-ethnography, and economic assessment [2024]
  • The impact of community delivery of intermittent preventive treatment of malaria in pregnancy on its coverage in four sub-Saharan African countries (Democratic Republic of the Congo, Madagascar, Mozambique, and Nigeria): a quasi-experimental multicentre evaluation [2023]
  • Prevalence of molecular markers of resistance to sulfadoxine-pyrimethamine before and after community delivery of intermittent preventive treatment of malaria in pregnancy in sub-Saharan Africa: a multi-country evaluation [2023]
  • Prevalence of malaria infection in pregnant women compared with children for tracking malaria transmission in sub-Saharan Africa: a systematic review and meta-analysis [2015]
  • Cost-effectiveness of two versus three or more doses of intermittent preventive treatment for malaria during pregnancy in sub-Saharan Africa: a modelling study of meta-analysis and cost data [2015]

• Lancet Infectious Diseases
  • Effect of Plasmodium falciparum sulfadoxine-pyrimethamine resistance on the effectiveness of intermittent preventive therapy for malaria in pregnancy in Africa: a systematic review and meta-analysis [2019]

• Malaria Journal
  • WHO antenatal care policy and prevention of malaria in pregnancy in sub-Saharan Africa [2024]
  • Multi-country review of ITN routine distribution data: are ANC and EPI channels achieving their potential? [2022]
  • Motivators and demotivators to accessing malaria in pregnancy interventions in sub-Saharan Africa: a meta-ethnographic review [2022]
  • Impact of Plasmodium falciparum malaria and intermittent preventive treatment of malaria in pregnancy on the risk of malaria in infants: a systematic review [2019]
  • Cost-effectiveness of malaria preventive treatment for HIV-infected pregnant women in sub-Saharan Africa [2017]
  • Factors affecting providers' delivery of intermittent preventive treatment for malaria in pregnancy: a five-country analysis of national service provision assessment surveys [2014]
  • Assessment of the consistency of national-level policies and guidelines for malaria in pregnancy in five African countries [2014]
  • Why are IPTp coverage targets so elusive in sub-Saharan Africa? A systematic review of health system barriers [2013]
  • Prevention and management of malaria during pregnancy: findings from a comparative qualitative study in Ghana, Kenya and Malawi [2013]
  • Ownership and use of insecticide-treated nets during pregnancy in sub-Saharan Africa: a review [2013]

• Parasite Epidemiology and Control
  • Prevalence of malaria parasitaemia in school-aged children and pregnant women in endemic settings of sub-Saharan Africa: A systematic review and meta-analysis [2020]

• PLoS Medicine
  • Mortality, Morbidity, and Developmental Outcomes in Infants Born to Women Who Received Either Mefloquine or Sulfadoxine-Pyrimethamine as Intermittent Preventive Treatment of Malaria in Pregnancy: A Cohort Study [2016]

• PLoS ONE
  • A systematic review and meta-analysis of asymptomatic malaria infection in pregnant women in Sub-Saharan Africa: A challenge for malaria elimination efforts [2021]
  • Social and Cultural Factors Affecting Uptake of Interventions for Malaria in Pregnancy in Africa: A Systematic Review of the Qualitative Research [2011]

• Seminars in Perinatology
  • Update of pre- and postnatal iron supplementation in malaria endemic settings [2019]

• Trends in Parasitology
  • Targeting pregnant women for malaria surveillance [2019]

• Tropical Medicine & International Health
  • Intermittent preventive treatment of malaria in pregnancy: at the crossroads of public health policy [2011]

• Tropical Medicine and Infectious Disease
  • Impact of Health Systems on the Implementation of Intermittent Preventive Treatment for Malaria in Pregnancy in Sub-Saharan Africa: A Narrative Synthesis [2020]

Sudan

• Journal of Infection in Developing Countries
  • A perspective of the epidemiology of malaria and anaemia and their impact on maternal and perinatal outcomes in Sudan [2011]

Tanzania

• BMC Public Health
  • Predictors for uptake of intermittent preventive treatment of malaria in pregnancy (IPTp) in Tanzania [2015]

• Lancet Global Health
  • Estimating malaria burden among pregnant women using data from antenatal care centres in Tanzania: a population-based study [2019]

• Malaria Journal
  • The potential of pregnant women as a sentinel population for malaria surveillance [2019]
  • Assessment of the impact of availability and readiness of malaria services on uptake of intermittent preventive treatment in pregnancy (IPTp) provided during ANC visits in Tanzania [2019]

Uganda

• BMC Pregnancy and Childbirth
  • A new strategy and its effect on adherence to intermittent preventive treatment of malaria in pregnancy in Uganda [2013]

• Drugs in R&D
  • Trimester-Specific Population Pharmacokinetics and Other Correlates of Variability in Sulphadoxine–Pyrimethamine Disposition Among Ugandan Pregnant Women [2015]

• Malaria Journal
  • Uptake of intermittent preventive treatment of malaria in pregnancy using sulfadoxine-pyrimethamine (IPTp-SP) in Uganda: a national survey [2022]
  • Factors associated with uptake of optimal doses of intermittent preventive treatment for malaria among pregnant women in Uganda: analysis of data from the Uganda Demographic and Health Survey, 2016 [2019]
  • Treatment and prevention of malaria in pregnancy in the private health sector in Uganda: implications for patient safety [2016]
  • Intermittent use of sulphadoxine-pyrimethamine for malaria prevention: a cross-sectional study of knowledge and practices among Ugandan women attending an urban antenatal clinic [2014]

United Kingdom

• Royal College of Obstetricians and Gynaecologists
  • The Diagnosis and Treatment of Malaria in Pregnancy [2010]

• UK Health Security Agency
  • Malaria: guidance, data and analysis
  • Malaria prevention guidelines for travellers from the UK

United States

• Centers for Disease Control and Prevention
  • Malaria Surveillance — United States, 2018 [2022]
  • Updated CDC Recommendations for Using Artemether-Lumefantrine for the Treatment of Uncomplicated Malaria in Pregnant Women in the United States [2018]
  • Malaria

• National Academies of Sciences, Engineering, and Medicine
  • Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis [2020]

• Obstetrical & Gynecological Survey
  • Malaria in Pregnancy: What the Obstetric Provider in Non-endemic Areas Needs to Know [2019]

WHO

• World Health Organization
  • WHO Guidelines for malaria [2024]
  • Safety of artemisinin and non-artemisinin antimalarials in the first trimester of pregnancy: review of evidence [2024]
  • Malaria vaccine: WHO position paper – May 2024 [2024]
  • World malaria report 2023 [2023]
  • WHO Malaria Policy Advisory Group (MPAG) meeting [2023]
  • Technical consultation to assess evidence on community-based delivery of intermittent preventive treatment in pregnancy for malaria [2023]
  • Monoclonal antibodies for malaria prevention. Preferred product characteristics and clinical development considerations [2023]
  • Malaria chemoprevention. Preferred product characteristics [2023]
  • Community deployment of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine a field guide [2023]
  • WHO technical consultation on preferred product characteristics for drugs used in malaria chemoprevention [2022]
  • WHO meeting on preferred product characteristics for monoclonal antibodies for malaria prevention [2022]
  • Malaria vaccines: preferred product characteristics and clinical development considerations [2022]
  • Malaria vaccine: WHO position paper – March 2022 [2022]
  • Global framework for the response to malaria in urban areas [2022]
  • Report on antimalarial drug efficacy, resistance and response: 10 years of surveillance (2010-2019) [2020]
  • Malaria surveillance, monitoring and evaluation: a reference manual [2018]
  • Implementing malaria in pregnancy programs in the context of World Health Organization recommendations on antenatal care for a positive pregnancy experience [2018]
  • Meeting report of the Evidence Review Group on malaria in pregnancy [2017]
  • WHO policy brief for the implementation of intermittent preventive treatment of malaria in pregnancy using sulfadoxine-pyrimethamine (IPTp-SP) [2013]
  • Meeting report of the Evidence Review Group on intermittent preventive treatment (IPT) of malaria in pregnancy [2013]
  • Assessment of the safety of artemisinin compounds in pregnancy [2007]
  • Malaria: Fact sheet
  • Malaria
  • Global Malaria Programme

WHO Eastern Mediterranean Region

• WHO Eastern Mediterranean Region
  • Malaria action plan for the Eastern Mediterranean Region, 2022-2030 [2023]

{Related topics}

• Topic
  • Neonatal infections
  • Infections in pregnancy