Systematic review and implementation research

Module 4

Systematic review and implementation research

Training course in research methodology, research protocol development and scientific writing 2025

September 24, 2025 - Geneva

Assignment

Part 1 (25 marks)

Question 1

Read the abstract, background and method of the systematic review below.

Segal TR, Giudice LC. Systematic review of climate change effects on reproductive health. Fertil Steril. 2022 Aug;118(2):215-23.

Answer the following questions (6 marks):

1.1 What was the aim of this study?

1.2 What sources were searched to retrieve the relevant articles in the review?

1.3 What were the criteria for inclusion of a study in the review?

1.4 What were the criteria for exclusion of a study from the review?

Question 2

Read the abstract, introduction and method of the systematic review below.

van Weelden W, Wekker V, de Wit L, Limpens J, Ijäs H, van Wassenaer-Leemhuis AG, Roseboom TJ, van Rijn BB, DeVries JH, Painter RC. Long-Term Effects of Oral Antidiabetic Drugs During Pregnancy on Offspring: A Systematic Review and Meta-analysis of Follow-up Studies of RCTs. Diabetes Ther. 2018 Oct;9(5):1811-1829.

Answer the following questions (6 marks):

2.1 What was the aim of the study?

2.2 What Databases were searched to retrieve the related articles?

2.3 What analysis were used for extracted data and qualitative assessment?

Question 3

Read the abstract and method of the implementation research below.

Parashar R, Gupt A, Bajpayee D, Gupta A, Thakur R, Sangwan A, Sharma A, Sharma D, Gupta S, Baswal D, Taneja G, Gera R. Implementation of community based advance distribution of misoprostol in Himachal Pradesh (India): lessons and way forward. BMC Pregnancy and Childbirth. 2018 Oct 29;18(1):428.

Answer the following questions (6 marks):

3.1 What was the aim of the study? What were the key activities of the implementation program?

3.2 What key variables were measured to understand the achievement of the implementation framework?

Question 4

Read the abstract and method of the implementation research below.

Mitchell SG, Schwartz RP, Kirk AS, Dusek K, Oros M, Hosler C, Gryczynski J, Barbosa C, Dunlap L, Lounsbury D, O'Grady KE, Brown BS. SBIRT Implementation for Adolescents in Urban Federally Qualified Health Centers. J Subst Abuse Treat. 2016 Jan;60:81-90.

Answer the following questions (7 marks):

4.1 What implementation program was examined in this article?

4.2 What was/were the objective(s) of the study?

4.3 What were the two SBIRT implementation arms compared?

4.4 Mention two of the implementation strategies used in the program.

4.5 What were the implementation outcomes of the study?

Part 2

Reflect over the topic, question and study design for your research protocol, revise if necessary and submit to your coach for review and feedback.